Abstract：Streptomyces is important resource for antibiotic research and development. Among the 1,000 kinds of microbial bioactive substances so far, more than 2/3 of these metabolites were produced by Streptomyces. Streptomyces albireticuli MDJK11 and Streptomyces albofavus MDJK44 were isolated from the rhizosphere soil of peony which showed potential characteristics as plant growth-promoting rhizobacteria. The whole genome sequencing combined with bioinformatics analysis of the two Streptomyces species revealed their abundant and novel secondary metabolic biosynthesis gene clusters. In this paper, the structural types and biological activities of secondary metabolites isolated and predicted based on genome information of the two Streptomyces species were summarized to provide references for the further development.
张琳1 常恺莉1 姚感2 杜秉海2 梅显贵1,*. Streptomyces albireticuli和Streptomyces albofavus次生代谢产物的研究进展
[J]. 中国抗生素杂志, 2021, 46(02): 89-96.
Zhang Lin1, Chang Kai-li1, Yao Gan2, Du Bing-hai2 and Mei Xian-gui1. Research progress on secondary metabolites of Streptomyces albireticuli and Streptomyces albofavus. CJA, 2021, 46(02): 89-96.
