Abstract：Cancer is the second largest cause of death after cardiovascular disease, leading to millions of deaths annually. Anticancer agents are crucial for the treatment of cancers, but the low specificity of the current accessible drugs usually results in various side effects. Moreover, the increasing emergency of drug-resistant cancers makes the anticancer agents less and less effective. Thus, it is imperative to develop novel anticancer agents. The anticancer activity of bis-indolic alkaloids diversities is well known, due to their novel structure, excellent bioactivity, high selectivity, and low side effects. This review focused on the recent research progress of bis-indolic alkaloids diversities as potential anticancer agents.
王丽平 邓桂英* 徐沙丽. 双吲哚类生物碱的抗肿瘤活性研究进展[J]. 中国抗生素杂志, 2021, 46(02): 97-103.
Wang Li-ping, Deng Gui-ying and Xu Sha-li. Research progress of bis-indolic alkaloids diversities as potential anticancer agents. CJA, 2021, 46(02): 97-103.